Zepbound

Zepbound is a medication used for weight loss and weight management, particularly in adults with obesity or overweight with weight-related medical problems. It’s a once-weekly injection that helps reduce body weight by ¹ ²:
– *Mechanism of Action*: Activating both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors, which slow down stomach emptying, reduce appetite, and increase feelings of fullness.

*Uses:*
– Chronic weight management in adults with obesity (BMI ≥ 30 kg/m²) or overweight (BMI ≥ 27 kg/m²) with at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol
– Treatment of moderate to severe obstructive sleep apnea (OSA) in adults with obesity

*Dosage and Administration:*
– Initial dose: 2.5 mg injected subcutaneously once weekly for 4 weeks
– Maintenance dose: 5 mg, 10 mg, or 15 mg injected subcutaneously once weekly
– Maximum dose: 15 mg injected subcutaneously once weekly

*Common Side Effects:*
– Nausea (25%)
– Diarrhea (19%)
– Constipation (17%)
– Indigestion (9%)
– Vomiting (8%)
– Injection reactions (6%)
– Tiredness (5%)
– Hair loss (5%)

*Cost and Availability:*
– Available as single-dose pens or vials in various strengths (2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg per 0.5 mL)
– Cost varies depending on insurance plan and pharmacy, with estimated costs ranging from $25 to $499 for a vial
– Savings cards and coupons may be available to reduce costs ¹ ²